2,3-dihydroxybenzoate 2,3-dioxygenase

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In enzymology, a 2,3-dihydroxybenzoate 2,3-dioxygenase (EC 1.13.11.28) is an enzyme that catalyzes the chemical reaction

2,3-dihydroxybenzoate + O₂ $\rightleftharpoons$ 2-carboxy-cis,cis-muconate

Thus, the two substrates of this enzyme are 2,3-dihydroxybenzoate and O₂, whereas its product is 2-carboxy-cis,cis-muconate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O₂. The systematic name of this enzyme class is 2,3-dihydroxybenzoate:oxygen 2,3-oxidoreductase (decyclizing). This enzyme is also called 2,3-dihydroxybenzoate 2,3-oxygenase.

[edit] References

IUBMB entry for 1.13.11.28
BRENDA references for 1.13.11.28 (Recommended.)
PubMed references for 1.13.11.28
PubMed Central references for 1.13.11.28
Google Scholar references for 1.13.11.28
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Sharma HK, Vaidyanathan CS (1975). "A new mode of ring cleavage of 2,3-dihydroxybenzoic acid in Tecoma stans (L.). Partial purification and properties of 2,3-dihydroxybenzoate 2,3-oxygenase". Eur. J. Biochem. 56: 163–71. doi:10.1111/j.1432-1033.1975.tb02219.x. PMID 1175620.