2,3-dihydroxybenzoate-serine ligase

From Wikipedia, the free encyclopedia

In enzymology, a 2,3-dihydroxybenzoate-serine ligase (EC 6.3.2.14) is an enzyme that catalyzes the chemical reaction

ATP + 2,3-dihydroxybenzoate + L-serine products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine

The 3 substrates of this enzyme are ATP, 2,3-dihydroxybenzoate, and L-serine, whereas its two products are products of ATP breakdown and N-(2,3-dihydroxybenzoyl)-L-serine.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is 2,3-dihydroxybenzoate:L-serine ligase. Other names in common use include N-(2,3-dihydroxybenzoyl)-serine synthetase, and 2,3-dihydroxybenzoylserine synthetase.

[edit] References

• IUBMB entry for 6.3.2.14
• BRENDA references for 6.3.2.14 (Recommended.)
• PubMed references for 6.3.2.14
• PubMed Central references for 6.3.2.14
• Google Scholar references for 6.3.2.14
• Brot N, Goodwin J (1968). "Regulation of 2,3-dihydroxybenzoylserine synthetase by iron". J. Biol. Chem. 243: 510–3. PMID 4966114. 

[edit] External links

The CAS registry number for this enzyme class is 37318-63-1.

• IUBMB entry for 6.3.2.14

• KEGG entry for 6.3.2.14

• BRENDA entry for 6.3.2.14

• NiceZyme view of 6.3.2.14

• EC2PDB: PDB structures for 6.3.2.14

• PRIAM entry for 6.3.2.14

• PUMA2 entry for 6.3.2.14

• IntEnz: Integrated Enzyme entry for 6.3.2.14

• MetaCyc entry for 6.3.2.14

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047527: 2,3-dihydroxybenzoate-serine ligase

• AMIGO entry for GO code 0047527: 2,3-dihydroxybenzoate-serine ligase