16-hydroxysteroid epimerase

From Wikipedia, the free encyclopedia

In enzymology, a 16-hydroxysteroid epimerase (EC 5.1.99.2) is an enzyme that catalyzes the chemical reaction

16alpha-hydroxysteroid 16beta-hydroxysteroid

Hence, this enzyme has one substrate, 16alpha-hydroxysteroid, and one product, 16beta-hydroxysteroid.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on other compounds. The systematic name of this enzyme class is 16-hydroxysteroid 16-epimerase.

[edit] References

• IUBMB entry for 5.1.99.2
• BRENDA references for 5.1.99.2 (Recommended.)
• PubMed references for 5.1.99.2
• PubMed Central references for 5.1.99.2
• Google Scholar references for 5.1.99.2
• Dahm K, Lindlau M, Breuer H (1968). "[Steroid epimerase--a new enzyme of estrogen metabolism]". Biochim. Biophys. Acta. 159: 377–89. PMID 5657462. 

[edit] External links

The CAS registry number for this enzyme class is 37318-40-4.

• IUBMB entry for 5.1.99.2

• KEGG entry for 5.1.99.2

• BRENDA entry for 5.1.99.2

• NiceZyme view of 5.1.99.2

• EC2PDB: PDB structures for 5.1.99.2

• PRIAM entry for 5.1.99.2

• PUMA2 entry for 5.1.99.2

• IntEnz: Integrated Enzyme entry for 5.1.99.2

• MetaCyc entry for 5.1.99.2

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047524: 16-hydroxysteroid epimerase

• AMIGO entry for GO code 0047524: 16-hydroxysteroid epimerase