1-Amino-2-propanol

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1-Amino-2-propanol[1]
IUPAC name 1-Aminopropan-2-ol
Other names Isopropanolamine
Monoisopropanolamine
Threamine
Abbreviations MIPA
Identifiers
CAS number [78-96-6]
PubChem 4
SMILES CC(CN)O
Properties
Molecular formula C3H9NO
Molar mass 75.10966
Density 0.973 g/mL
Melting point

-2 °C, 271 K, 28 °F

Boiling point

160 °C, 433 K, 320 °F

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

1-Amino-2-propanol is a secondary amino alcohol. It can be prepared by the addition of aqueous ammonia to propylene oxide.

1-Amino-2-propanol is an intermediate in the synthesis of a variety of pharmaceutical drugs and is the very basic building block of the opioid, methadone.

[edit] Reactions

1-Dimethylamino-2-propanol can be synthesized via Eschweiler-Clarke methylation of 1-amino-2-propanol using formic acid and formaldehyde[citation needed].

[edit] See also

[edit] References

  1. ^ Amino-2-propanol at Sigma-Aldrich


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