(S,S)-butanediol dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a (S,S)-butanediol dehydrogenase (EC 1.1.1.76) is an enzyme that catalyzes the chemical reaction

(S,S)-butane-2,3-diol + NAD⁺ acetoin + NADH + H⁺

Thus, the two substrates of this enzyme are (S,S)-butane-2,3-diol and NAD⁺, whereas its 3 products are acetoin, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (S,S)-butane-2,3-diol:NAD+ oxidoreductase. Other names in common use include L-butanediol dehydrogenase, L-BDH, and L(+)-2,3-butanediol dehydrogenase (L-acetoin forming). This enzyme participates in butanoic acid metabolism.

[edit] References

• IUBMB entry for 1.1.1.76
• BRENDA references for 1.1.1.76 (Recommended.)
• PubMed references for 1.1.1.76
• PubMed Central references for 1.1.1.76
• Google Scholar references for 1.1.1.76
• Taylor MB and Juni E (1960). "Stereoisomeric specificities of 2,3-butanediol dehydrogenase". Biochim. Biophys. Acta 39: 448–457. doi:10.1016/0006-3002(60)90197-9. 

[edit] External links

The CAS registry number for this enzyme class is 37250-14-9.

• IUBMB entry for 1.1.1.76

• KEGG entry for 1.1.1.76

• BRENDA entry for 1.1.1.76

• NiceZyme view of 1.1.1.76

• EC2PDB: PDB structures for 1.1.1.76

• PRIAM entry for 1.1.1.76

• PUMA2 entry for 1.1.1.76

• IntEnz: Integrated Enzyme entry for 1.1.1.76

• MetaCyc entry for 1.1.1.76

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047512: (S,S)-butanediol dehydrogenase

• AMIGO entry for GO code 0047512: (S,S)-butanediol dehydrogenase