(R)-pantolactone dehydrogenase (flavin)

From Wikipedia, the free encyclopedia

In enzymology, a (R)-pantolactone dehydrogenase (flavin) (EC 1.1.99.27) is an enzyme that catalyzes the chemical reaction

(R)-pantolactone + acceptor 2-dehydropantolactone + reduced acceptor

Thus, the two substrates of this enzyme are (R)-pantolactone and acceptor, whereas its two products are 2-dehydropantolactone and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is (R)-pantolactone:acceptor oxidoreductase (flavin-containing). Other names in common use include 2-dehydropantolactone reductase (flavin), 2-dehydropantoyl-lactone reductase (flavin), and (R)-pantoyllactone dehydrogenase (flavin).

[edit] References

• IUBMB entry for 1.1.99.27
• BRENDA references for 1.1.99.27 (Recommended.)
• PubMed references for 1.1.99.27
• PubMed Central references for 1.1.99.27
• Google Scholar references for 1.1.99.27
• Kataoka M, Shimizu S, Yamada H (1992). "Purification and characterization of a novel FMN-dependent enzyme Membrane-bound L-(+)-pantoyl lactone dehydrogenase from Nocardia asteroides". Eur. J. Biochem. 204: 799–806. doi:10.1111/j.1432-1033.1992.tb16698.x. PMID 1541293. 

[edit] External links

The CAS registry number for this enzyme class is 140879-14-7.

• IUBMB entry for 1.1.99.27

• KEGG entry for 1.1.99.27

• BRENDA entry for 1.1.99.27

• NiceZyme view of 1.1.99.27

• EC2PDB: PDB structures for 1.1.99.27

• PRIAM entry for 1.1.99.27

• PUMA2 entry for 1.1.99.27

• IntEnz: Integrated Enzyme entry for 1.1.99.27

• MetaCyc entry for 1.1.99.27

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047060: (R)-pantolactone dehydrogenase (flavin)

• AMIGO entry for GO code 0047060: (R)-pantolactone dehydrogenase (flavin)