(protein-PII) uridylyltransferase

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In enzymology, a [protein-PII] uridylyltransferase (EC 2.7.7.59) is an enzyme that catalyzes the chemical reaction

UTP + [protein-PII] $\rightleftharpoons$ diphosphate + uridylyl-[protein-PII]

Thus, the two substrates of this enzyme are UTP and [[[protein-PII]]], whereas its two products are diphosphate and [[uridylyl-[protein-PII]]].

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:[protein-PII] uridylyltransferase. Other names in common use include PII uridylyl-transferase, and uridyl removing enzyme. This enzyme participates in two-component system - general.

[edit] References

IUBMB entry for 2.7.7.59
BRENDA references for 2.7.7.59 (Recommended.)
PubMed references for 2.7.7.59
PubMed Central references for 2.7.7.59
Google Scholar references for 2.7.7.59
Garcia E, Rhee SG (1983). "Cascade control of Escherichia coli glutamine synthetase Purification and properties of PII uridylyltransferase and uridylyl-removing enzyme". J. Biol. Chem. 258: 2246–53. PMID 6130097.
van Heeswijk WC, Rabenberg M, Westerhoff HV, Kahn D (1993). "The genes of the glutamine synthetase adenylylation cascade are not regulated by nitrogen in Escherichia coli". Mol. Microbiol. 9: 443–57. doi:10.1111/j.1365-2958.1993.tb01706.x. PMID 8412694.