(myosin-light-chain) phosphatase

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In enzymology, a [myosin-light-chain] phosphatase (EC 3.1.3.53) is an enzyme that catalyzes the chemical reaction

[myosin light-chain] phosphate + H₂O $\rightleftharpoons$ [myosin light-chain] + phosphate

Thus, the two substrates of this enzyme are myosin light-chain phosphate and H₂O, whereas its two products are [[[myosin light-chain]]] and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is [myosin-light-chain]-phosphate phosphohydrolase. Other names in common use include myosin light chain kinase phosphatase, myosin phosphatase, myosin phosphatase, protein phosphatase 2A, and myosin-light-chain-phosphatase.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1S70.

[edit] References

IUBMB entry for 3.1.3.53
BRENDA references for 3.1.3.53 (Recommended.)
PubMed references for 3.1.3.53
PubMed Central references for 3.1.3.53
Google Scholar references for 3.1.3.53
Pato MD, Adelstein RS (1983). "Purification and characterization of a multisubunit phosphatase from turkey gizzard smooth muscle. The effect of calmodulin binding to myosin light chain kinase on dephosphorylation". J. Biol. Chem. 258: 7047–54. PMID 6304072.