Zbtb7

From Wikipedia, the free encyclopedia

Zbtb7, originally named Pokemon, is a gene that may act as a master switch for cancer. The leader of the research team which discovered this, geneticist Pier Paolo Pandolfi from the Memorial Sloan-Kettering Cancer Center (MSKCC) in New York City, said the gene is unique in that it is needed for other oncogenes to cause cancer.[1] Discovery of the gene was first published in the January 2005 issue of Nature.[2]

The original name, Pokemon, stands for "POK erythroid myeloid ontogenic factor" and is most likely a backronym of the Pokémon media franchise. Nintendo subsidiary Pokémon USA, not wanting the bad press inherent with its trademark sharing a name with a cancer-causing gene, threatened the center with legal action in December 2005, at which point MSKCC decided to rename it as Zbtb7.[3]

[edit] Genes


[edit] References

  1. ^ Jai A. Dennison. "Switching Off 'Pokemon' Gene May Block Cancer-Cell Formation", Daily News Central, 2005-01-20. Retrieved on June 27, 2006.
  2. ^ Takahiro Maeda, Robin M. Hobbs, et al. (2005-01-20). "Role of the proto-oncogene Pokemon in cellular transformation and ARF repression". Nature (433): 278-285. DOI:10.1038/nature03203. Retrieved on 2006-06-27. 
  3. ^ Brendan Sinclair (2005-12-19). Pokemon USA threatens to sue cancer researchers. GameSpot. Retrieved on June 27, 2006.
 This biochemistry article is a stub. You can help Wikipedia by expanding it.
Retrieved from "http://en.wikipedia.org../../../z/b/t/Zbtb7.html"
In other languages