Talk:Xanthine oxidase

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the effect of xanthine oxidase activities on ethanol metabolism

[edit] From the article

Xanthine oxidase is really the product of a proteolytic cleavage of the enzyme xanthine dehydrogenase, which occurs in tissues under conditions of oxygen starvation. When oxygen supply is restored to the tissue, xanthine oxidase activity continues, and the result is the liberation of free radicals that can cause the injury known as "ischemic reperfusion damage." Xanthine oxidase is the first enzyme known that completely reverses its catalytic activity upon modification by proteases.

This sounds like waffle. JFW | T@lk 19:47, 27 Apr 2005 (UTC)

[edit] Bovine Xanthine Oxidase

Anyone know about the effects of homogenisation of milk on Bovine Xanthine Oxidase. Non-digestion and damage to blood vessels caused by activity on plasmogen in artery walls.

[edit] Homogenization and ingested XO

This article talks about the idea that homogenization causes fat globules to surround XO and somehow avoid the natural breakdown of this enzyme into its base amino acids in the stomach, allowing it passage into the bloodstream, where it somehow causes heart damage. So umm... should I include this? Can someone hopefully tell me where this theory is wrong? Wouldn't fat globules simply be digested? I can't see how it would somehow perfectly seal off an enzyme and not deconstruct it, because I thought fats were broken down into fatty acids and reassembled. Tyciol 06:00, 10 December 2006 (UTC)