Talk:West Nile virus
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[edit] Added text
Added text from public domain resource at http://www.cdc.gov/ncidod/dvbid/westnile/ -- Anon.
- Industry dominates the disease definition. Non-orthodox research is not allowed to be linked here. Toxicological correlations for this disease may be seen here www.geocities.com/noxot
- Could someone please tell me why it's so worrisome, especially considering that influenza kills at least 100 times more people per year in the US? - user:Montrealais
In the same vein as Montrealais I'm going to add some dissenting viewpoints about spraying and the media attention given to this thing. -- wji
Disproportionate media coverage?
While i'll submit that there has been much more media concern over WNV than something like influenza, WNV is a virus that we can easily eradicate if people would take the right precautions. People who think that WNV is just an exaggerated problem are the same people who refuse to get vaccinated for polio. It's because of them that polio still exists in the world today.
It's also worth noting that even though WNV isn't currently an epidemic, malaria(which shares very similar modes of transmission) is.
The statements as to why there is disproportionate media coverage are biased at best. I don't think it's appropriate to be stating one side or another, so i won't be including my thoughts either.
genius86
If this is so widespread around the world, does anyone have numbers on how many it kills in other countries each year? Thius page could use more balance. --rmhermen
replaced 'Some have speculated that fears of West Nile are due to xenophobia.' Some may have, but since the disease is not spread by 'foreigners', it's a silly speculation and simply false. I think what was probably meant is that it was a disease not native to the areas where it is currently reported. Someone else
In the "control" section, some statements are made that just don't seem right. "The government has also taken it upon itself to spray entire communities with massive amounts of insect repellent although they do not address the fact that spraying the air with dangereous chemicals may in fact do much more harm than the West Nile Virus." Which one does "The government" refer to? I'm assuming US, but it should say. Also, what "dangerous" chemicals are used? The author of the paragraph assumes some knowledge, but does not share it.
This duplicate page was created at "West Nile Virus": I have turned it into a redirect, bacause this article appears to cover everything in the duplicate.
West Nile Virus
User "69.209.201.10" has This article is a stub. You can help Wikipedia by fixing it.
West Nile Virus is a flavivirus commonly found in Africa, West Asia, and the Middle East. It is closely related to St. Louis encephalitis virus found in the United States. The virus can infect humans, birds, mosquitoes, horses and some other mammals.
“West Nile fever is a case of mild disease in people, characterized by flu-like symptoms. West Nile fever typically lasts only a few days and does not appear to cause any long-term health effects.
More severe disease due to a person being infected with this virus can be “West Nile encephalitis,” West Nile meningitis or West Nile meningoencephalitis.” Encephalitis refers to an inflammation of the brain, meningitis is an inflammation of the membrane around the brain and the spinal cord, and meningoencephalitis refers to inflammation of the brain and the membrane surrounding it.[1]
[edit] Links
- Centers for Disease Control (US) web site: [2]
Why isn't there an effective vaccine or treatment for West Nile Virus in humans? If there have been deaths by this disease, shouldn't our medical scientists have found a way to treat, or at least vaccine the disease?
- It has killed thousands but malaria and AIDS have killed millions and we don't have vaccines against them yet either. They are working on it, though. Rmhermen 01:21, Apr 2, 2005 (UTC)
- many vaccines are on the horizon. Antibodies against other flaviviruses have proven to be effective against WNV, however investment in research isn't very economical. Pharm companies would rather wait for it to be an epidemic, then cash in.genius86
Re US outbreak: user 69.209.201.10 has removed reference to source being due to an air traveller, and instead has stated that could have leaked from Plum Island and that Donald Rumsfeld had sold it to Saddam Hussein. I've no idea whether this might be true - it just sounds possibly dodgy. Finbarr Saunders 05:32, 15 August 2005 (UTC)
- I can remember New York City local news reporting suspicions that the 1999 West Nile virus outbreak in the New York City area resulted from a deliberate release of the virus by the government of Iraq. The suspicions apparently arose due to the ATCC's and/or CDC's known sale of West Nile virus to Iraq during the 1980s (see United States and weapons of mass destruction). Shouldn't we at least mention the suspicions of Iraqi involvement - if only in one line?168.122.84.213 13:40, 17 October 2006 (UTC)
[edit] Re-wrote first paragraph
Added more details about mammals and clearer statement about main route of transmission. In later section added occupational exposure as documented route of transmission--FloNight 04:07, 15 December 2005 (UTC)
[edit] Outdated
This article is seriously outdated there is 2005 information on the CDC site. I'm too lazy to update all of the article myself though. And a factual error. Here [3] CDC tells there were 9862 reported human cases and 264 deaths in 2003. While in the article it states this: "In the 2003 outbreak, 9,858 cases and 262 deaths were reported by the CDC".
- About the supposed factual error, please note that the CDC continues to update it numbers (both up and down) months even years after the fact. About the lack of 2005 numbers, I am the one who usually updates them. In the early stages I updated the numbers monthly or more frequently but I later decided it was just too many edits. I will update it now but note that large changes to the 2005 will continue until about June of next year. Rmhermen 04:39, 23 December 2005 (UTC)
Allright, but i suppose those numbers are things the external reviewers count as an error.(83.118.38.37 21:38, 22 January 2006 (UTC))
- No those things are listed below. Rmhermen 23:41, 22 January 2006 (UTC)
[edit] Errors ID'd by Nature, to correct
The results of what exactly Nature suggested should be corrected is out... italicize each bullet point once you make the correction. -- user:zanimum
- Stiff neck or menimgismus is actually a very rare finding with WNV
- Blood banks in the US are routinely screening for WNV in their donor pools during epidemic season.
- In the diagnostic assay, although cross-reactive antibodies are a problem for the ELISA, the diagnosis can be secured by an additional functional (neutralization) test
- 2nd Par in 'History' - Many birds are infected. Corvids are more suscectible to lethal infection
- The bit about immunohistochenistry staining is misleading – the virus shows up brown because of a substrate-enzyme reaction
I notice that someone just removed the statement about "stiff neck" as a symptom. Note that the reviewer didn't say this was never a symptom, just that it was very rare. If this is the case, please put in some statement about how often this symptom occurs.
In general, please don't just remove disputed statements. Do some homework so that you can replace them with a more accurate description. For one thing, this will prevent someone else from ignorantly re-inserting the same misconception in a year or two. —Steven G. Johnson 01:04, 23 December 2005 (UTC)
- About point 2, I presume this must be a "error of omission" as the article says nothing about American blood banks at all. About point 4, the 2nd paragraph of the history section has read "and many birds—especially crows and other corvids—are infected." for several years. Is the problem the lack of a mention of extra mortality of corvids? Mortality is discussed nowhere in that paragraph for any species. Rmhermen 04:35, 23 December 2005 (UTC)
- I have corrected the stiff neck sentence. Interestingly the reviewer spelt meningismus incorrectly. Onco_p53 02:38, 28 December 2005 (UTC)
[edit] Errors in virion description
I rewrote the introduction that describes the virus particle reconstructions. These are not the same as photgraphs. Moreover, WN particles are remarkably similar to those of dengue. AND, could someone please tell me where that strange purple picture came from? What is it supposed to represent? Lindenb 21:07, 3 April 2006 (UTC)
- The image is claimed to be of West Nile virus and uploaded from the NIAID. The American Society for Microbiology also used this image with that caption in 2003[4]. Rmhermen 21:18, 3 April 2006 (UTC)
[edit] citations needed
A citation is needed that west nile virus can infect all the species listed in the opening paragraph. —The preceding unsigned comment was added by 74.97.51.123 (talk) 00:35, 8 January 2007 (UTC).
- Citations are generally avoided in the lead section. Rmhermen 02:48, 8 January 2007 (UTC)
- WP:Lead recommends that the lead of the article not present any new information, but only summarize what is in the article. On that theory, it could be argued that citations would not be needed in the lead. However, that breaks down if the information in the lead is NOT also in body of the article. In this case, it is not. If you search for "chipmunk" for instance, you will see that this word is only in the lead of the article. This is just one example. This information needs to be cited. Johntex\talk 02:57, 6 March 2007 (UTC)
[edit] Symptoms
The article does not seem to include anything on the effects on humans. What are the symptoms? Is it fatal? If so, what is the mortality rate? How long does the disease typically take to present and to progress to completeion? Can someone knowledgeable please add this information to the article? Johntex\talk 02:53, 6 March 2007 (UTC)
[edit] Recent Toronto article
There was a recent Toronto Star article about new information of how the virus spreads - in particular, something like 80% of cases in Toronto were within several kilometres of an urban park/urban forest. Does anyone know how to find it online? It was older than a week, but fairly recent. Esn 09:30, 29 March 2007 (UTC)
