Vesicular-tubular cluster

From Wikipedia, the free encyclopedia

You have new messages (last change).
There are very few or no other articles that link to this one.
Please help introduce links in articles on related topics. After links have been created, remove this message.
This article has been tagged since November 2006.
This article or section is in need of attention from an expert on the subject.
Please help recruit one or improve this article yourself. See the talk page for details.
Please consider using {{Expert-subject}} to associate this request with a WikiProject

vesicular-tubular cluster:

An intermediate compartment mediating trafficking between the endoplasmic reticulum and Golgi complex. COPII vesicles that have budded from exit sites in the endoplasmic reticulum lose their coats and fuse to form the vesicular-tubular cluster (VTC). Retrieval (or retrograde) transport in COPI vesicles returns many of the lost ER resident proteins back to the endoplasmic reticulum. Forward (or anterograde) transport moves the VTC contents to the cis-Golgi network, the receiving face of the Golgi complex. This process is thought to occur by one of two processes. One is known as cisternal maturation where the VTC simply matures into the cis-Golgi network. In another COPI vesicular transport moves VTC material to the receiving face of the Golgi apparatus. A fuller explanation of the two processes is described (see Golgi complex). Evidence exists for both processes and it may be that both occur simultaneously in cells.

Retrieved from "http://en.wikipedia.org../../../v/e/s/Vesicular-tubular_cluster.html"