Vanillyl mandelic acid

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Vanillyl mandelic acid
IUPAC name 2-hydroxy-2-(4-hydroxy-3-methoxy-
phenyl)acetic acid
Identifiers
CAS number [55-10-7]
PubChem 1245
MeSH Vanilmandelic+acid
Properties
Molecular formula C9H11NO4
Molar mass 197.188 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Vanillyl mandelic acid (VMA) is a chemical end product of catecholamine metabolism. It is found in urine together with homovanillic acid (HVA). In timed urine tests its quantity (concentration μg /24 h) is assessed, along with creatinine clearance, and the concentration of cortisols, catecholamines, and metanephrines.

Urinary levels of vanillyl mandelic acid are raised in pheochromocytoma, a tumor of catecholamine-secreting chromaffin cells.