Ureidopenicillin
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The ureidopenicillins are a group of penicillins which are also active against Pseudomonas aeruginosa. There are three ureidopenicillins in clinical use:
They're mostly ampicillin derivatives in which the D-side amino chain has been converted to a variety of ureas. It is speculated that the added side chain mimics a longer segment of the peptidoglycan chain more than ampicillin and thus would make it bind more easily to the penicillin-binding proteins. They are not resistant to beta-lactamases.
They're used parenterally with particular usage on Gram negative bacteria.
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