Type II cytokeratin

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Type II cytokeratins constitutes the Type II intermediate filaments (IFs) of the intracytoplasmatic cytoskeleton, which is present in all mammalian epithelial cells. The type 2 cytokeratins consist of basic or neutral, high molecular weight proteins which 'in vivo' are arranged in pairs of heterotypic Type I and Type II keratin chains, coexpressed during differentiation of simple and stratified epithelial tissues.

Type II cytokeratins are encoded on chromosome 12q and encompasses: CK1, CK2, CK3, CK4, CK5, CK6, CK7 and CK8. Their molecular weight ranges from 52 kDa (CK8) to 67 kDa (CK18).

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v • d • e
Proteins of the cytoskeleton

Microfilaments: Actins - Myosins - Actin-binding proteins

Intermediate filaments: type 1 and 2 Cytokeratin (type I, type II)
type 3 Desmin, GFAP, Peripherin, Vimentin
type 4 Internexin, Nestin, Neurofilament
type 5 Lamin (A, B)

Microtubules: Dyneins - Kinesins - MAPs (Tau protein) - Tubulins

Prokaryotic cytoskeleton: Crescentin - FtsZ - MreB

Other: Major Sperm Proteins

v • d • e
Protein: fibrous proteins

Collagen (Type-I, Type-II, Type-III, Type-IV, Type-XVIII) - Elastin - Cytoskeletal

Keratin: Cyto- (Type I, Type II), type I ( 10, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21), type II ( 1, 2A, 3, 4, 5, 6A, 7, 8, 9), Hair (Type I, Type II), Beta

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