Tumor hypoxia

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Tumor hypoxia is the situation where tumor cells have been deprived of oxygen. They are relevant in the study of radiation therapy as they can be made more susceptible to treatment by increasing the amount of oxygen in them. Study of tumors in such conditions was pioneered by Dr L. H. Gray.

It can also be a result of the high degree of cell proliferation undergone in tumor tissue, causing a higher cell density, and thus taxing the local oxygen supply.