Talk:Tumor necrosis factor-alpha
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I found some historical information here. JFW | T@lk 12:00, 11 December 2005 (UTC)
--- why is it called 'tumor necrosis factor' -- some background would be good, I'll see what I can find --hmackiernan
"Inhibition of TNFα promotes the inflammatory response, which in turn causes many of the clinical problems associated with autoimmune disorders such as rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, and psoriasis. These disorders are sometimes treated by inhibiting TNFα "
This seems contradictory. If inhibition of TNFa promotes the inflammatory response, why would you treat these conditions by inhibiting TNFa??
I noticed the above contradiction as well and think the first part of the phrase must be an error. However, I'm not a medical expert, so I don't dare edit the TNF page.
I removed the offending phrase (as I am about to refer people to the page). Out of curiosity, I just went back and checked the history. It was clearly an editing glitch, with the phrase left over from what is now covered in the second sentence. -- Bob Kerns
[edit] viral replication
doesnt tnf block instead of cause viral replication??? -Sucrine ( ><> talk) 14:52, 19 January 2007 (UTC)
How about Tumor Necrosis Factor beta? It is not discussed at all in this page. TNF-alpha is involved in Toxic Shock Syndrome among other things. I can't find any decent (recent) reviews on the topic.
