Trousseau's sign of malignancy
From Wikipedia, the free encyclopedia
Trousseau's sign of malignancy is a medical sign. It is also referred to as "Trousseau's syndrome" to distinguish it from Trousseau sign of latent tetany.
Some malignancies, especially adenocarcinomas of the pancreas and lung, are associated with hypercoagulability for reasons that remain unclear. In patients with malignancy-associated hypercoagulable states, the blood may spontaneously form clots in the portal vessels, the deep veins of the extremities, or the superficial veins anywhere on the body. When recurrent clots form in different superficial veins around the body, this is described as migratory thrombophlebitis. Armand Trousseau first described this finding in himself; he was subsequently found to have pancreatic cancer.
