Tropicamide
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Tropicamide
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| Systematic (IUPAC) name | |
| N-ethyl-3-hydroxy-2-phenyl-N- (pyridin-4-ylmethyl) propanamide | |
| Identifiers | |
| CAS number | |
| ATC code | S01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C17H20N2O2 |
| Mol. mass | 284.353 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 45% |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Tropicamide (troe-PIK-a-mide) is an acetylcholine receptor blocker, (a muscarinic antagonist). It is used to dilate (enlarge) the eye's pupil in order to allow better examination of the lens, vitreous humor, and retina. It is typically used during eye examinations, but may also be used before or after eye surgery.
Application of tropicamide can produce short acting mydriasis and cycloplegia.
Tropicamide, a parasympatholytic, is occasionally administered in eye drops in combination with hydroxyamphetamine (brand name Paremyd®), which is a sympathomimetic. The use of drugs stimulating multiple divisions of the autonomic nervous system ensures the dilation the pupil without opposing muscle group firing.
Tropicamide effects on the pupil can last from 6 - 8 hours.
[edit] See also
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