Tricaine methanesulfonate

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Tricaine Methane Sulphonate MS-222 is a fish anesthetic and muscle relaxant that operates by preventing action potentials. By blocking action potentials, no signals can be exchanged between the brain and the extremities. There will be no sensory input or muscle contractions which would have been caused by action potential, which includes most muscles.

MS-222 is the only anesthetic licensed in the United States for fin fish that is intended for human consumption.

MS-222 is acidic in water, so care must be taken to prevent a highly acidic solution.

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