Thymidylate synthase
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thymidylate synthetase
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Identifiers | |
Symbol | TYMS TS |
HUGO | 12441 |
Entrez | 7298 |
OMIM | 188350 |
RefSeq | NM_001071 |
UniProt | P04818 |
Other data | |
EC number | 2.1.1.45 |
Locus | Chr. 18 p11.31-11.21 |
Thymidylate synthase is an enzyme used to generate dihydrofolate to create thymidine triphosphate.
As one of the targets in chemotherapy, it can be inhibited by fluorouracil.