Thomas Anantharaman

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Thomas Anantharaman is a computer statistician specializing in Bayesian inference approaches for NP complete problems. He is best known for his work with Feng-hsiung Hsu on the Chess playing computers ChipTest and Deep Thought at Carnegie Mellon University. This work was the foundation for the IBM chess-playing computer Deep Blue which beat world champion Garry Kasparov in 1997.

In 1985, Carnegie Mellon University graduate students Feng-hsiung Hsu, Thomas Anantharaman, Murray Campbell and Andreas Nowatzyk used spare chips they'd found to put together a chess-playing machine that they called ChipTest. By 1987, the machine, integrating some innovative ideas about search strategies, had become the reigning computer chess champion. A successor, Deep Thought, using two special-purpose chips, plus about 200 off-the-shelf chips, working in parallel, achieved grandmaster-level play. [[1]].

This was the foundation for Thomas Anantharaman's 1990 PhD Dissertation from Carnegie Mellon University: "A Statistical Study of Selective Min-Max Search in Computer Chess"

Following this work, he has focused his attentions into the field of biostatistics and the application of Bayesian methods to the analysis of single molecule Optical Mapping technologies.

  • Anantharaman T, Mishra B, Schwartz D (1999). "Genomics via optical mapping. III: Contiging genomic DNA.". Proc Int Conf Intell Syst Mol Biol: 18-27. PMID 10786282. 
  • Anantharaman T, Mishra B, Schwartz D (1997). "Genomics via optical mapping. II: Ordered restriction maps.". J Comput Biol 4 (2): 91-118. PMID 9228610.