TAS2R16

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TAS2R16 (taste receptor, type 2, member 16) is a human gene that encodes for a receptor that may play a role in the perception of bitterness. Variants of this gene have been linked to an increased risk for alcohol dependence.

The TAS2R16 gene is located on the long (q) arm of chromosome 7 at position 31.1 - 31.3, from base pair 122,228,764 to base pair 122,229,639.

[edit] References

Hinrichs AL, Wang JC, Bufe B, Kwon JM, Budde J, Allen R, Bertelsen S, Evans W, Dick D, Rice J, Foroud T, Nurnberger J, Tischfield JA, Kuperman S, Crowe R, Hesselbrock V, Schuckit M, Almasy L, Porjesz B, Edenberg HJ, Begleiter H, Meyerhof W, Bierut LJ, Goate AM (2006). "Functional Variant in a Bitter-Taste Receptor (hTAS2R16) Influences Risk of Alcohol Dependence". Am J Hum Genet 78 (1): 103-11. PMID 16385453.
Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet 32 (3): 397-401. PMID 12379855.
Drewnowski A (2001). "The science and complexity of bitter taste". Nutr Rev 59 (6): 163-9. PMID 11444592.