Image:Synaptonemal complex.png

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Description

The Synaptonemal Complex. (A) Model of the SC. Lateral elements (light blue rods) of homologous chromosomes align and synapse together via a meshwork of transverse filaments (black lines) and longitudinal filaments (dark blue rods). The longitudinal filaments are collectively referred to as the “central element” of the SC. Ellipsoidal structures called recombination nodules (gray ellipsoid) are constructed on the central region of the SC. As their name implies, recombination nodules are believed to be involved in facilitating meiotic recombination (crossing over). The chromatin (red loops) of each homologue is attached to its corresponding lateral element. Because there are two “sister chromatids” in each homologue, two loops are shown extending laterally from each point along a lateral element. (B) Top: Set of tomato SCs. Chromatin “sheaths” are visible around each SC. Bottom: Two tomato SCs. The chromatin has been stripped from the SCs, allowing the details of the SC to be observed. Each SC has a kinetochore (“ball-like” structure) at its centromere. Recombination nodules, ellipsoidal structures found on the central regions of SCs, mark the sites of crossover events (see inset).

Source

Hey J: What's So Hot about Recombination Hotspots? PLoS Biol 2/6/2004: e190. http://dx.doi.org/10.1371/journal.pbio.0020190

Date

Published: June 15, 2004

Author

Images and legend courtesy of Daniel G. Peterson, Mississippi Genome Exploration Laboratory, Mississippi State University, Mississippi State, Mississippi, United States (http://www.msstate.edu/research/mgel/index.htm).

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