Talk:Suxamethonium chloride
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[edit] Page in mess!!!
This page introduces total confusion between succinylcholine and its chloride. Those two MUST BE SEPARATED! Either there is a chlorine in the molecule or not, the name must reflect it! This looks like a major rework or redirects, etc. I leave then only an alert here. Sometimes Wikipedia is scary!
- I have tagged the article accordingly. By the way, for future reference, please sign your comments. Thank you for the feedback. 38.100.34.2 17:18, 28 March 2007 (UTC)
- As far as I know, succinylcholine is presented with chloride as a counterion to maintain neutrality, as it is a charged molecule. Is there anything else you feel could be improved on this page? I would appreciate more feedback. Fvasconcellos 00:40, 3 April 2007 (UTC)
[edit] Naming
One dose frequently used in clinical practice is 2 mg/kg. (At least that is the dose I usually use in my clinical practice). John Doyle. (djdoyle)
I guess the substance under discussion is Succinylbischoline (with a "bis" in it) aka Suxamethonium. I´m not entirely sure which of the two is correct so I won´t change it right now. Could somebody please check the proper pharmacological name? Kosebamse 12:54 Jan 28, 2003 (UTC)
I think the only "proper" name is the IUPAC chemical name, which is not in everyday use. Suxamethonium, scoline, and succinylcholine seem to be the commonest names this compound is referred by - Malcolm Farmer
I looked it up in a pharmacology textbook and the substance is listed under succinylbischoline (with a bis). But it's true that in everyday use it is succinylcholine (without a bis) or even succi so I really don't know where it should properly go. With hypertext however I believe it might be feasible to have substances dealt with under their IUPAC name and have common names linked there. Perhaps there is a wikipedia policy for this? Kosebamse
My pharm book has it listed as Succinylcholine. My vote on the "proper" name would be the International Nonproprietary Name which is set by the WHO. I don't know if Succinylcholine is the INN or the USAN (My book is american).Matt 04:38, 23 Jun 2004 (UTC)
- It seems that the INN is suxamethonium chloride with CAS no. 71-27-2.
Far more common than malignant hyperthermia and prolonged block is anaphylaxis. I thought that it was implicated in anaphylaxis more than any other anaesthetic drug and that this was the leading cause of death due to it's use. Should we not edit the page to reflect this in the side effect paragraph?
[edit] Tom Clancy's "Teeth of the Tiger"
This drug--spelled succinylcholine throughout the book--is used to assassinate several "bad guys" in Clancy's 2003 novel Teeth of the Tiger, though the symptoms and speed of death (cardiac arrest) vary somewhat from the description in the article. --Robertkeller 23:28, 11 September 2006 (UTC)
[edit] History
A nice, freely accessible review which may help with the writing of a "History" section. Fvasconcellos 01:12, 3 April 2007 (UTC)