Sulfamethizole
From Wikipedia, the free encyclopedia
Sulfamethizole
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Systematic (IUPAC) name | |
4-amino-N-(5-methyl-1,3,4-thiadiazol-2-yl)- benzenesulfonamide | |
Identifiers | |
CAS number | |
ATC code | B05 D06BA04, J01EB02, S01AB01 |
PubChem | |
DrugBank | |
Chemical data | |
Formula | C9H10N4O2S2 |
Mol. mass | 270.333 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Protein binding | 98–99% |
Metabolism | ? |
Half life | 3–8 hours |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | ? |
Sulfamethizole is a sulfonamide antibiotic.
[edit] External links
- Ratanajamit C, Skriver M, Nørgaard M, Jepsen P, Schønheyder H, Sørensen H (2003). "Adverse pregnancy outcome in users of sulfamethizole during pregnancy: a population-based observational study.". J Antimicrob Chemother 52 (5): 837-41. PMID 14519675.
- Kerrn M, Frimodt-Møller N, Espersen F (2003). "Effects of sulfamethizole and amdinocillin against Escherichia coli strains (with various susceptibilities) in an ascending urinary tract infection mouse model.". Antimicrob Agents Chemother 47 (3): 1002-9. PMID 12604534.
- Watanabe H, Hastings J (1990). "Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine.". Biochim Biophys Acta 1017 (3): 229-34. PMID 2372557.
Mafenide, Prontosil, Sulfacetamide, Sulfamethizole, Sulfamethoxazole (with Trimethoprim in Co-trimoxazole), Sulfanilimide, Sulfasalazine, Sulfisoxazole