Stereospecificity
From Wikipedia, the free encyclopedia
In chemistry, stereospecificity is the property of a chemical reaction that yields different stereoisomeric reaction products from two stereoisomeric reactants depending on the reaction conditions.
For example, the addition of dibromocarbene to cis-2-butene yields cis-2,3-dimethyl-1,1-dibromocyclopropane whereas addition of dibromocarbene to the trans isomer exclusively yields the trans cyclopropane.
Chiral synthesis is built on stereospecific reactions where also the optical activity of a chemical compound is preserved.
Another example is disrotatory ring closing reaction trans-cis-trans-2,4,6-octatriene to cis-dimethylcyclohexadiene.
[edit] See also
[edit] References
- Skell, P.S. and Garner, A.Y. Journal of the American Chemical Society. 78, 3409 (1956)
