Staphylococcal scalded skin syndrome
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| ICD-10 | L00 |
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Staphylococcal scalded skin syndrome, SSSS, also known as Pemphigus neonatorum or Ritter's disease, is a dermatological condition caused by Staphylococcus aureus. The syndrome is induced by 2 epidermolytic exotoxins A and B, which are released by S. aureus and cause the epidermis to detach from the underlying dermis. One of the exotoxins is produced by the bacterial chromosome, while the other is produced by a plasmid. Bacterial plasmids are pieces of self-replicating DNA that often code for secondary characteristics, such as antibiotic resistance, and toxin production.
The symptoms somewhat mimic advanced arthritis and disorders of the nervous system, and can include severe and constant pain, loss of motor functions (such as severe stuttering when speaking) clinical depression and insomnia.
[edit] Ritter's Disease of the Newborn
Ritter's Disease of the Newborn is the most severe form of SSSS with signs and symptoms equivalent to that of SSSS.
[edit] Reference
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