Spinal Cord Stimulator

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Spinal Cord Stimulator (SCS) or Dorsal Column Stimulator (DCS) is an implantable medical device used to treat chronic pain of neurologic origin. An electric impulse generated by the device near the dorsal surface of the spinal cord provides a paresthesia ("tingling") sensation that alters the perception of pain by the patient. A surgeon introduces the spinal cord stimulator lead into the epidural space either by percutaneous approach or by surgical laminectomy or laminotomy. A pulse generator or RF receiver is implanted in the abdomen or buttocks. A wire harness connects the lead to the pulse generator.

Spinal cord stimulator leads in thoracic spine
Spinal cord stimulator leads in thoracic spine

Contents

[edit] History

First report of a spinal cord stimulator implantation was in 1967 by Shealy.[1] Studies since then have demonstrated efficacy of SCS in relieving select chronic pain disorders including failed back syndrome, complex regional pain syndrome and peripheral neuropathy.

Randomized controlled trials have shown efficacy of spinal cord stimulator in failed-back syndrome.[2]

[edit] Surgical Procedure

Complications are generally related to the surgical procedure and can include lead migration, infection, epidural hematoma, paralysis, dural tap, and in extremely rare cases, death. The possibility of lead migration is lessened when placed by laminectomy.[3]

A trial is usually done before the permanent unit is placed. A temporary percutaneous lead is used and is connected to an external pulse generator. The trial is from 3 to 7 days. If the patient has at least 50% improvement in pain during the trial, the patient is considered a candidate for the permanent unit.


[edit] Cautions

Patients with SCS units are not able to have MRI procedures due to heating of the implanted electrodes which can cause spinal cord damage. Other medical scans such as ultrasound, CT and plain x-ray can be performed.

People with SCS should avoid areas and performing tasks which are linked with strong electromagnetic interference, examples incluide electricity substations and activities such as arc welding.

[edit] Types of Equipment

There are three types of SCS units:

  • Conventional Implantable Pulse Generator (IPG) consists of a battery and control electronics. When the battery wears out, it is surgically replaced. Battery life is generally 2 to 3 years, but can sometimes be much less.
  • Rechargeable Implantable Pulse Generator (IPG) consists of a rechargeable battery and control electronics. The battery is recharged by an external device worn for a few hours every two to three weeks. Eventually the IPG will need to be replaced, but far less frequently than a conventional IPG. One such device carries a 25 year warrantee in the European Union.
  • Radio Frequency (RF) device consists of an implanted receiver and a transmitter device worn like a cell phone. The transmitter sends RF energy to the receiver which in turn sends stimulation to the lead. RF units are generally used when a lower level of stimulation is needed.

The patient is provided a remote control to turn on and off the stimulator, and depending on the device and the surgeon's preference, allows for limited programming of the stimulation patterns. The surgeon has a programming device that provides a wide range of stimulation settings.

[edit] Current and Voltage Configuration

SCS comes in constant current, variable voltage (Advanced Bionics and ANS) or constant voltage, variable current (Medtronic). Conventional SCS devices utilized a single-source model whereby stimulation is achieved. Advanced Bionics' Precision IPG introduced the concept of a multiple source constant current design. This design is such that any scarring that occurs on the leads which can be variable in space and time can be overcome by a system whose sources automatically adapt for the scarring. This results in non-variable stimulation as the dynamic scarring process continues.

[edit] Proposed mechanisms of action

Among the proposed mechanism of action of SCS in pain relief include [4]

  • "closing of the gate" by the antidromic activation of large-diameter afferent fibers (see gate-control theory of pain)
  • activation of supraspinal loops relayed by the brain stem or thalamocortical systems providing both ascending and descending inhibition
  • activation of anterior pretectal nucleus which has descending pain inhibitory influces on lower segments
  • suppression of wide-dynamic-range (WDR) neurons responsive to sensory input

[edit] Other Uses

SCS units have been used to treat patients with frequent migraines. The leads are implanted in the bilateral suboccipital region.[5]

[edit] Trivia

  • Jerry Lewis has a spinal cord stimulator for his intractable low back pain and is a spokesperson for Medtronic.[6]
  • Medtronic SCS allows scuba diving to a depth of 30 feet (9.14 meters).
  • Michael Roman, a chronic pain sufferer who had his leg amputated due to an infection, is now restarting his career as a professional racecar driver. Roman was implanted with the Precision system, and his racing team is sponsored by Boston Scientific.

[edit] See also

[edit] References

  1. ^ Shealy CN, Mortimer JT, Reswick, JB (1967). "Electrical Inhibition of pain by stimulation of the dorsal columns: Preliminary Clinical Report". Anesth Analg 46: 489-91. PMID 4952225. 
  2. ^ North RB, Ewend MG, Lawton MT, Kidd DH, Piantadosi S (1991). "Failed back surgery syndrome: 5-year follow-up after spinal cord stimulator implantation". Neurosurgery 28 (5): 692-9. PMID 1831547. 
  3. ^ Villavicencio AT, Leveque JC, Rubin L, Bulsara K, Gorecki JP (2000). "Laminectomy versus percutaneous electrode placement for spinal cord stimulation". Neurosurgery 46 (2): 399-405; discussion 405-6. PMID 10690729. 
  4. ^ Oakley JC, Prager JP (2002). "Spinal cord stimulation: mechanisms of action". Spine 27: 2574-83. PMID 12435996. 
  5. ^ Matharu MS, Bartsch T, Ward N, Frackowiak RS, Weiner R, Goadsby PJ (2004). "Central neuromodulation in chronic migraine patients with suboccipital stimulators: a PET study". Brain 127 (Pt 1): 220-30. PMID 14607792. 
  6. ^ http://www.webmd.com/content/chat_transcripts/1/103993.htm

[edit] Additional references

  • Mailis-Gagnon A, Furlan AD, Sandoval JA, Taylor R (2004). "Spinal cord stimulation for chronic pain". Cochrane Database Syst Rev (3): CD003783. PMID 15266501. 
  • North RB, Kidd DH, Farrokhi F, Piantadosi SA (2005). "Spinal cord stimulation versus repeated lumbosacral spine surgery for chronic pain: a randomized, controlled trial". Neurosurgery 56 (1): 98-106; discussion 106-7. PMID 15617591. 

[edit] External links

[edit] Manufacturers

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