Spermidine
From Wikipedia, the free encyclopedia
| Spermidine | |
|---|---|
 |
|
| Systematic name | N-(3-aminopropyl)butane-1,4-diamine N-(3-aminopropyl)-1,4-diaminobutane |
| Chemical formula | C7H19N3 |
| Molecular mass | 145.25 g/mol |
| CAS number | [124-20-9] |
| SMILES | NCCCNCCCCN |
| Properties | |
| Density | 0.925 g/mL at 25 °C |
| Melting point | 22-25.0 °C |
| Boiling point | xx.x °C |
| Refractive index | n20/D 1.479(lit.) |
| Foreign activity | DNase, RNase, and protease, none detected |
| Storage temp. | 2-8°C |
| Disclaimer and references | |
Spermidine is a polyamine involved in cellular metabolism that can be used to stimulate the enzyme, T7 rna polymerase, a type of RNA polymerase.
Contents |
[edit] Biochemical actions
- Inhibits neuronal nitric oxide synthase (nNOS).
- Binds and precipitates DNA.
- May be used for purification of DNA binding proteins.
- Stimulates T4 polynucleotide kinase activity.
[edit] Safety
Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.
