Spasmodic dysphonia

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Spasmodic dysphonia (or laryngeal dystonia) is a voice disorder characterized by involuntary movements of one or more muscles of the larynx (vocal folds or voice box) during speech. Individuals who have spasmodic dysphonia may have occasional difficulty saying a word or two or they may experience sufficient difficulty to interfere with communication. Spasmodic dysphonia causes the voice to break or to have a tight, strained or strangled quality.

Spasmodic dysphonia can affect anyone. The first signs of this disorder are found most often in individuals between 30 and 50 years of age. Women, more than men, appear to be affected by spasmodic dysphonia.

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[edit] Types of spasmodic dysphonia

The three types of spasmodic dysphonia are adductor spasmodic dysphonia, abductor spasmodic dysphonia and mixed spasmodic dysphonia.

[edit] Adductor spasmodic dysphonia

In adductor spasmodic dysphonia, sudden involuntary muscle movements or spasms cause the vocal folds (or vocal cords) to slam together and stiffen. These spasms make it difficult for the vocal folds to vibrate and produce voice. Words are often cut off or difficult to start because of the muscle spasms. Therefore, speech may be choppy and sound similar to stuttering. The voice of an individual with adductor spasmodic dysphonia is commonly described as strained or strangled and full of effort. Surprisingly, the spasms are usually absent while whispering, laughing, singing, speaking at a high pitch, in rhyme, as experienced by Dilbert creator Scott Adams, or speaking while breathing in. Stress, however, often makes the muscle spasms more severe.

[edit] Abductor spasmodic dysphonia

In abductor spasmodic dysphonia, sudden involuntary muscle movements or spasms cause the vocal folds to open. The vocal folds cannot vibrate when they are open. The open position of the vocal folds also allows air to escape from the lungs during speech. As a result, the voices of these individuals often sound weak, quiet and breathy or whispery. As with adductor spasmodic dysphonia, the spasms are often absent during activities such as laughing or singing.

[edit] Mixed spasmodic dysphonia

Mixed spasmodic dysphonia involves muscles that open the vocal folds as well as muscles that close the vocal folds and therefore has features of both adductor and abductor spasmodic dysphonia.

[edit] Origins

The exact cause of spasmodic dysphonia is unknown. Because the voice can sound normal or near normal at times, and because there are no organic signs to the illness, there is debate as to whether spasmodic dysphonia is psychogenic, that is, originating in the affected person's mind rather than from a physical cause. Seifert and Kollbrunner state in their review that "Psychogenic causes, a 'psychological disequilibrium', and an increased tension of the laryngeal muscles are presumed to be one end of the spectrum of possible factors leading to the development of the disorder" (PMID 16220409). According to National Institute on Deafness and Other Communication Disorders "research has revealed increasing evidence that most cases of spasmodic dysphonia are in fact neurogenic or having to do with the nervous system (brain and nerves)", although they don't give any evidence for their statement.

Spasmodic dysphonia may co-occur with other movement disorders such as blepharospasm (excessive eye blinking and involuntary forced eye closure), tardive dyskinesia (involuntary and repetitious movement of muscles of the face, body, arms and legs), oromandibular dystonia (involuntary movements of the jaw muscles, lips and tongue), torticollis (involuntary movements of the neck muscles), or tremor (rhythmic, quivering muscle movements).

In some cases, spasmodic dysphonia may run in families and is thought to be inherited. Research has identified a possible gene on chromosome 9 that may lead to the development of spasmodic dysphonia that is common in families. While self-report anecdotal data suggest that in some individuals the voice symptoms began following an upper respiratory infection, injury to the larynx, a long period of voice use, studies have demonstrated that none of these "causes" are greater than what would be expected for the population at large.

[edit] Diagnosis

The diagnosis of spasmodic dysphonia is usually made based on identifying the way the symptoms developed as well as by careful examination of the individual. Most people are evaluated by a team that usually includes an otolaryngologist (a physician who specializes in ear, nose and throat disorders), a speech-language pathologist (a professional trained to diagnose and treat speech, language and voice disorders) and a neurologist (a physician who specializes in nervous system disorders). The otolaryngologist examines the vocal folds to look for other possible causes for the voice disorder. Fiberoptic nasolaryngoscopy, a method whereby a small lighted tube is passed through the nose and into the throat, is a helpful tool that allows the otolaryngologist to evaluate vocal cord movement during speech. The speech-language pathologist evaluates the patient's voice and voice quality. The neurologist evaluates the patient for signs of other muscle movement disorders.

[edit] Treatment

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There is no cure for spasmodic dysphonia. Current treatments help reduce the symptoms of this voice disorder. Voice therapy may reduce some symptoms, especially in mild cases. An operation that cuts the recurrent laryngeal nerve of the vocal folds has improved the voice of many for several months to several years but the improvement is often temporary. Others may benefit from psychological counseling to help them to accept and live with their voice problem. Still others may benefit from job counseling that will help them select a line of work more compatible with their speaking limitations. Diane Rehm, of National Public Radio, and Robert F. Kennedy Jr., of Air America Radio, have managed to continue their careers in radio despite having the disorder.

The most effective treatment for reducing the symptoms of spasmodic dysphonia is injections of very small amounts of botox directly into the affected muscles of the larynx. The toxin weakens muscles by blocking the nerve impulse to the muscle. The botox injections generally improve the voice for a period of three to four months after which the voice symptoms gradually return. Reinjections are necessary to maintain a good speaking voice. Initial side effects that usually subside after a few days to a few weeks may include a temporary weak, breathy voice or occasional swallowing difficulties. Botox may relieve the symptoms of both adductor and abductor spasmodic dysphonia.

Morton Cooper claims to have been curing the condition for 35 years with a treatment he calls DVR. His treatments are not widely accepted in the medical community; in response, instead of verifying his results, he alleges that information about spasmodic dysphonia is controlled by Allergan, the maker of Botox, producing a conflict of interest. However, studies have demonstrated the effectiveness of Botox. Mr. Cooper's methods are not subject to peer review and his improvements or cures have not be validated by reputable medical practitioners.[citation needed]

[edit] Famous people with spasmodic dysphonia

[edit] References

  1. ^ Scott Adams (2006-10-24). Good News Day. Posted on 'Dilbert.blog'.
  2. ^

[edit] External links

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