Slow reacting substance of anaphylaxis

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The Slow reacting substance of of anaphylaxis or SRS-A is a mixture of the leukotrienes LTC4, LTD4 and LTE4. Mast cells secrete it during the anaphylactic reaction, inducing inflammation. (Dorlands) It induced prolonged, slow contraction of smooth muscle and has a major bronchoconstrictor role in asthma. (Morris)

[edit] References

  1. Dorland's Medical Dictionary. Retrieved on December 15, 2006.
  2. Howard R. Morris, Graham W. Taylor, Priscilla J. Piper, John R. Tippins. Structure of slow-reacting substance of anaphylaxis from guinea-pig lung. Retrieved on December 15, 2006.
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