Samuel Denmeade

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Dr. Samuel Ray Denmeade is an oncologist at the Johns Hopkins University School of Medicine.

In addition to being an oncologist, he maintains an active research interest in novel ways to treat prostate cancer. He has been a key researcher in a number of cancer treatments, including engineering the bacterial toxin Aerolysin to target cancer cells. Other research includes the study of proteases, with the theory that a lethal drug could be disguised as a prodrug and only released when exposed to the enzymatic activity of PSA, PSA being present in its enzymatically active form only in the tumor and not elsewhere in the body.

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