Ross River virus

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Ross River virus
Virus classification
Group: Group IV ((+)ssRNA)
Family: Togaviridae
Genus: Alphavirus
Species: Ross River virus

Ross River virus (RRV) is an arbovirus of the genus Alphavirus. In humans, it is the cause of an 'epidemic polyarthritis' commonly known as Ross River fever, that in Australia infected an average of about 4,000 people annually in the decade 1995-2004 [1]. Ross River fever is a notifiable disease in Australia (see List of notifiable diseases#Australia).

Ross River virus is endemic to Australia and Papua New Guinea, and was observed in an outbreak in the South Pacific during 1979-1980. It was named following the isolation of an arbovirus from mosquitoes trapped beside Ross River, near Townsville, Queensland, in 1959, and the subsequent identification of this virus as the one responsible for cases of epidemic polyarthritis in Queensland and New South Wales. Outbreaks as long ago as 1928 are now attributed to Ross River virus. [3]

Ross River fever is also known as Ross River virus infection or Ross River virus disease, since not all patients experience symptoms of fever. A review of a number of studies concluded that between 20% and 60% of patients experience fever. Similarly, the name epidemic polyarthritis fell out of use because arthritic symptoms are not observed in all patients; the same review found that between 83% and 98% of patients experienced joint pain. Other symptoms include rash. Although there is some (mostly) anecdotal evidence of long-term chronic effects due to Ross River virus, particularly joint pain, patients can typically expect to recover within a month after the onset of symptoms. (See [3] for more details.)

In rural and regional areas of Australia, the continued prevalence of Ross River virus is thought to be supported by 'reservoir' hosts such as large marsupial mammals, but antibodies to Ross River virus have been found in a wide variety of placental and marsupial mammals, and also in a number of bird species. It is not presently known what reservoir hosts support Ross River virus in metropolitan areas such as Brisbane. [3]

[edit] References

  1. Communicable Diseases Australia, National Notifiable Diseases Surveillance System.
  2. Information on RRV from a company that produces test kits for RRV antibodies.
  3. D. Harley, A. Sleigh, and S. Ritchie (2001). Ross River Virus Transmission, Infection, and Disease: a Cross-Disciplinary Review. Clinical Microbiology Reviews, 14(4):909-932.

[edit] External links