Rhinoscleroma

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Rhinoscleroma
Classification & external resources
ICD-9 040.1
DiseasesDB 31327
eMedicine derm/831 
MeSH C01.252.400.310.503.650

Rhinoscleroma is a chronic granulomatous disease of the upper respiratory tract.

Contents

[edit] Synonyms

Mikulicz disease

[edit] Incidence

More females than males are affected. Patients are usually 10 to 30 years of age. Mostly seen in Africa and central America. Less in United States. common in tropical countries.

[edit] Causes

It is caused by Klebsiella rhinoscleromatis.

[edit] Symptoms

[edit] Historical background

Photogravure of rhinoscleroma from Wolkowitsch.
Photogravure of rhinoscleroma from Wolkowitsch.

First described by Hans von Hebra (1847-1902) in a paper titled Ueber ein eigenthümliches Neugebilde an der Nase; Rhinosclerom; nebst histologischem Befunde vom Dr. M. Kohn, published in the January 1870 issue of the Wiener Medizinische Wochenschrift (vol. 20, pp. 1-5). Hans was the son of the Czech born dermatologist Ferdinand Ritter von Hebra (1816-1880), founder of the New Vienna School of Dermatology.

M. Kohn, who did the histology for the paper, is the name by birth of Moritz Kaposi (1837-1902).










[edit] Treatment

Tetracycline or ciprofloxacillin

[edit] Prognosis

It is not lethal in nature.

[edit] See also