Retinol binding protein 4
From Wikipedia, the free encyclopedia
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retinol binding protein 4, plasma
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| Identifiers | |
| Symbol | RBP4 |
| HUGO | 9922 |
| Entrez | 5950 |
| OMIM | 180250 |
| RefSeq | NM_006744 |
| UniProt | P02753 |
| Other data | |
| Locus | Chr. 10 q24 |
Retinol binding protein 4 (RBP4) has recently been described as an adipokine that contributes to insulin resistance in the AG4KO mouse model.[1]
It is secreted by adipocytes, and can act as a signal to other cells, when there is a decrease in plasma glucose concentration.[2]
[edit] See also
[edit] References
- ^ Yang, Q. et al. (2005) Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 436:35-362
- ^ Herman, M.A and Kahn, B.B. (2006) Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony. The Journal of Clincial Investigation. 116:1767-1775 link
