Renal compensation
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Renal compensation is a mechanism by which the kidneys can regulate the plasma pH. It is slower than respiratory compensation, but has a greater ability to restore normal values.
In respiratory acidosis, the kidney produces and excretes ammonium (NH4+) and monophosphate, generating bicarbonate in the process while clearing acid.[1]
In respiratory alkalosis, less HCO3- is reabsorbed, thus lowering the pH.[2]
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Filtration: Ultrafiltration - Countercurrent exchange
Hormones affecting filtration:Antidiuretic hormone (ADH) - Aldosterone - Atrial natriuretic peptide
Endocrine: Renin - Erythropoietin (EPO) - Calcitriol (Active vitamin D) - Prostaglandins
Assessing Renal function / Measures of dialysis: Glomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product
Fluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap
Bicarbonate buffering system - Respiratory compensation - Renal compensation