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[edit] We need a Pluto Talk

Agonists, inverse agonists, antagonists, functional selectivity. There are too many variations in individual definitions of all of these. I often hear inverse agonists being described as antagonists by knowledgable people in pharmacology, because when they were educated, there was nothing other than the on / off dogma associated with the terms. The problem in clarification extends too to binding sites of receptors. There should be a difference in name between agonists which work at the same binding site of a receptor and those which do not. I hereby motion that we raise this issue, whether it be here on wikipedia or in a conference to discuss this issue so that the confusion does not continue into the future.--Carlwfbird 05:16, 26 September 2006 (UTC)

Does the non-competetive antagonist bind to a different site on the SAME RECEPTOR, or to a different receptor? Eddietoran 01:34, 31 January 2007 (UTC)