Raine syndrome

From Wikipedia, the free encyclopedia

Raine syndrome (also called osteosclerotic bone dysplasia) is a rare disease in newborns characterized by craniofacial anomalies including microcephaly, exophthalmos, midface hypoplasia, cleft palate, gum hypertrophy and generalized osteosclerosis on radiography. It is usually lethal within a few hours after birth.

[edit] References

• Kan A, Kozlowski K (1992). "New distinct lethal osteosclerotic bone dysplasia (Raine syndrome).". Am J Med Genet 43 (5): 860-4. PMID 1642277. 
• Rejjal A (1998). "Raine syndrome.". Am J Med Genet 78 (4): 382-5. PMID 9714445. 
• Rickert C, Rieder H, Rehder H, Hülskamp G, Hörnig-Franz I, Louwen F, Paulus W (2002). "Neuropathology of Raine syndrome.". Acta Neuropathol (Berl) 103 (3): 281-7. PMID 11907809. 
• Al-Gazali L, Jehier K, Nazih B, Abtin F, Haas D, Sadagahatian R (2003). "Further delineation of Raine syndrome.". Clin Dysmorphol 12 (2): 89-93. PMID 12868469.