Rac1

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Rac1 belongs to the Rho family of GTPases. It is a pleiotropic regulator of many cellular processes, including the cell cycle, cell-cell adhesion, motility (through the actin network), and of epithelial differentiation (proposed to be necessary for maintaining epidermal stem cells).

See: Benitah SA et al., "Stem cell depletion through epidermal deletion of Rac1" Science 2005 Aug 5; 309(5736):933-935


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