R-type calcium channel
From Wikipedia, the free encyclopedia
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calcium channel, voltage-dependent, R type, alpha 1E subunit
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| Identifiers | |
| Symbol | CACNA1E CACNL1A6 |
| HUGO | 1392 |
| Entrez | 777 |
| OMIM | 601013 |
| RefSeq | NM_000721 |
| UniProt | Q15878 |
| Other data | |
| Locus | Chr. 1 q25-q31 |
The R-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit is the one that determines most of the channel's properties.
They are poorly understood, but like Q-type calcium channels, they appear to be present in cerebellar granule cells. They have a high threshold of activation and relatively slow kinetics.
[edit] External links
Stretch-activated ion channel - Ligand-gated ion channel - Voltage-gated ion channel
Ca: Voltage-dependent calcium channel (L-type/CACNA1C, N-type, P-type, Q-type, R-type, T-type) - Inositol triphosphate receptor - Ryanodine receptor - Cation channels of sperm
Na: Sodium channel: SCN4A - SCN5A - SCN9A - Epithelial sodium channel
K: Potassium channel: Voltage-gated (KvLQT1, HERG, Shaker gene, KCNE1) - Calcium-activated (BK channel, SK channel) - Inward-rectifier (ROMK, KCNJ2) - Tandem pore domain/Resting ion channel
Cl: Chloride channel: Cystic fibrosis transmembrane conductance regulator
Transient receptor potential (TRPV6) - Cyclic nucleotide-gated ion channel - Two-pore channel
