R&B number-one hits of 1949 (USA)
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This list of R&B #1 hits of 1949 in the United States is part of the List of #1 R&B hits (USA).
| 19 February | Boogie Chillen | John Lee Hooker | 1 week |
| 19 February | The Deacon's Hop | Big Jay McNeeley's Blue Jays | 1 week |
| 5 May | The Huckle-Buck | Paul Williams and His Hucklebuckers | 14 weeks* |
| 4 June | Trouble Blues | The Charles Brown Trio | 15 weeks |
| 20 August | Ain't Nobody’s Business (Parts 1 & 2) | Jimmy Witherspoon | 1 week |
| 10 September | Roomin' House Boogie | Amos Milburn | 2 weeks |
| 17 September | All She Wants to Do Is Rock | Wynonie Harris | 2 weeks* |
| 17 September | Tell Me So | The Orioles | 1 week |
| 24 September | Baby Get Lost | Dinah Washington | 2 weeks |
| 8 October | Beans and Corn Bread | Louis Jordan and His Tympany Five | 1 week |
| 15 October | Saturday Night Fish Fry | Louis Jordan and His Tympany Five | 12 weeks* |
| 24 December | For You My Love | Larry Darnell | 8 weeks* |
An asterisk (*) after a song title means that the song lost and then regained the number-one spot.
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1940 | 1941 | 1942 | 1943 | 1944 | 1945 | 1946 | 1947 | 1948 | 1949 |
