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Tripellenamine (Pyribenzamine) is a first generation antihistamine. It can be used in the treatment of asthma, hay fever, rhinitus and urticaria but is now less common as it has been replaced by newer antihistamines. This drug is sold in 50mg tablets, which are usually green in colour.
Pyribenzamine is a mildly sedating antihistamine. Other side effects can include gastrointestinal irritation, dry mouth, nausea and dizziness.
Pyribenzamine is sometimes abused recreationally in combination with the opiate pentazocine. It is dangerous to combine an opiate with a sedating antihistamine in this way.
CAS# 154-69-8
Antihistamines (primarily R06) |
Aminoalkyl ethers |
Bromazine, Carbinoxamine, Clemastine, Chlorphenoxamine, Diphenylpyraline, Diphenhydramine, Doxylamine |
Substituted alkylamines |
Brompheniramine, Chlorphenamine, Dexbrompheniramine , Dexchlorpheniramine, Dimetindene, Pheniramine, Talastine |
Substituted ethylene diamines |
Chloropyramine, Histapyrrodine, Mepyramine, Methapyrilene,Pyribenzamine |
Phenothiazine derivatives |
Alimemazine, Hydroxyethylpromethazine, Isothipendyl, Mequitazine, Methdilazine, Oxomemazine, Promethazine |
Piperazine derivatives |
Buclizine, Cetirizine, Chlorcyclizine, Cinnarizine, Cyclizine, Hydroxyzine, Levocetirizine, Meclozine, Niaprazine, Oxatomide |
Others for systemic use |
Acrivastine, Antazoline, Astemizole, Azatadine, Azelastine, Bamipine, Cyproheptadine, Deptropine, Desloratadine, Ebastine, Epinastine, Ketotifen, Loratadine, Mebhydrolin, Mizolastine, Phenindamine, Pimethixene, Pyrrobutamine, Rupatadine, Terfenadine, Triprolidine |
For topical use |
Bamipine, Chloropyramine, Chlorphenoxamine, Clemastine, Dimetindene, Diphenhydramine, Isothipendyl, Mepyramine, Promethazine, Thenalidine |
Antiallergic agents excluding corticosteroids |
Antazoline, Azelastine, Fexofenadine |
Other antiallergics |
Emedastine, Epinastine, Ketotifen, Olopatadine |