Puromycin
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Puromycin is an antibiotic that is a potent inhibitor of translation.
[edit] Inhibition of translation
Puromycin is an antibiotic that causes premature chain termination during translation. Part of the molecule resembles the 3' end of the aminoacylated tRNA. It will enter the A site and transfer to the growing chain, causing premature chain release.
It is not selective for either prokaryotes or eukaryotes.
Also of note, puromycin is critical in mRNA display as it allows the growing peptide chain to be covalently bonded to its own mRNA template.
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