Talk:Prothrombin time
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[edit] reference method
the reference method defining the test is a manually eyeballing test performed by mixing plasma from the sample with reagent and then look for the clot by looking for wrinkles on the samples surface when tilting the reaction vial and then record the time. All kept in a warm 37 degree bath.
the samples used for defining the reference sample comes from frosen down samples from the WHO.
81.170.221.51 21:55, 6 January 2007 (UTC)
[edit] external laboratory quality organisations
EQUALIS and SKUP and NOKLUS are some organisations that monitors labs externally by sending out samples to the laboratories and collecting results in order to see if the labs are genereating results comparable to each others.
[edit] optical vs. mechanical
"takes to clot is measured optically," Clots are also measured mechanically, even in this day in age. Most hospitals use (as a backup to optical systems) mechanical impedance methods in situations of extreme hemolysis/lipemia, when most wavelengths which measure clot formation would be affected by such interferences.
Just saying, and I didn't want to muck up such a great article by changing without discussing it first.
[edit] oops
OOPS!!, i think i got mixed up, extrinsic/intrinsic. Hahaha, serves me right for looking at internet references!, i'll just move some of it to APTT if need be. T 05:41, 11 Apr 2004 (UTC)
False alarm, it was just a one-off typo. Fixed. T 05:48, 11 Apr 2004 (UTC)
[edit] NPT
NPT "Near Patient Testing" is called POC "Point Of Care" in the dia-buisniess termnology.
I added a bit on NPT, as I felt this needed covering too. If I get round to it I might put a photo or two in. Please feel free to fiddle with this - I am an ex-wikipedian doing cold turkey and trying largely successfuly to stay away, so I won't be looking in here all that often, I hope! 82.35.17.203 18:25, 15 Nov 2004 (UTC)
- Nice one. If you're an ex-Wikipedian, couldn't you have inserted a few more links? :-) JFW | T@lk 22:29, 15 Nov 2004 (UTC)
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- heheh thank you. Unfortunately my status as an ex-wikipedian means I can give myself some confused moral letout which means I don't have to ... don't ask me to explain this, it'll never stand up in court. :) 82.35.17.203 20:25, 17 Nov 2004 (UTC)
Hi I am not sure how to add this citation on the Lupus Anticoagulant and the INR being off. But here is the Link to the article: http://www.annals.org/cgi/content/full/127/3/177. So do what you need to do with it. :)
[edit] Eponym & history
We should add the fact that this test was initially developed by Armand Quick[1]. JFW | T@lk 17:10, 1 June 2006 (UTC)
- Definitely, I still remember forms that said PTT (Quick's test) on them! -- Samir धर्म 01:38, 3 June 2006 (UTC)
That would have been incorrect :-). JFW | T@lk 20:17, 5 June 2006 (UTC)
[edit] Google
This page is number 4 on Google for "prothrombin time". Nice one. JFW | T@lk 20:18, 5 June 2006 (UTC)
[edit] Help for Citation re: LAC
Hi I am not sure how to add this citation on the Lupus Anticoagulant and the INR being off. But here is the Link to the article: http://www.annals.org/cgi/content/full/127/3/177. So do what you need to do with it. :)
[edit] Quick reference - the big lie
Countless articles refer to Quick's 1935 paper in J Biol Chem 109:73-4. Slight problem: J Biol Chem is fully available online, and the article doesn't seem to exist! I'd love to do some sleuthing, but somebody must have made up this reference!
Instead, I found Quick himself[2] referring to the Am J Med Sci article from 1935 which is similarly titled but probably exists (as opposed to the J Biol Chem article). How on earth could this have happened? JFW | T@lk 21:58, 9 November 2006 (UTC)
- a few sources cite it as J Biol Chem 109:LXXIII... Maybe the roman numerals mean that there was a separately paginated part in/of that issue (not available online)??
