Proprotein convertase 2
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proprotein convertase subtilisin/kexin type 2
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| Identifiers | |
| Symbol | PCSK2 NEC2 |
| HUGO | 8744 |
| Entrez | 5126 |
| OMIM | 162151 |
| RefSeq | NM_002594 |
| UniProt | P16519 |
| Other data | |
| Locus | Chr. 20 p11.2 |
Proprotein convertase 2 (PC2) is a serine protease and proprotein convertase It is also referred to as "prohormone convertase 2". PC2, like proprotein convertase 1 (PC1), is an enzyme responsible for the maturation of many neuroendocrine peptides from their precursors, such as the conversion of proinsulin to insulin. PC2 plays only a minor role in insulin biosynthesis, but a greater role in glucagon biosynthesis compared to PC1.
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This biochemistry article is a stub. You can help Wikipedia by expanding it. |
Trypsin - Chymotrypsin - Elastase (Neutrophil, Pancreatic) - Enteropeptidase
Acrosin - Pronase - Proprotein convertases (1, 2) - Subtilisin/Furin
Immune (Chymase, Granzyme, Tryptase, Proteinase 3/Myeloblastin) - Venombin (Ancrod, Batroxobin)
Complement system: Factor B - Factor D - Factor I - MASP (MASP1, MASP2)
Coagulation factors: Thrombin - Factor VIIa - Factor IXa - Factor Xa - Factor XIa - Factor XIIa - Kallikrein (PSA) - Fibrinolysis: Plasmin - Tissue plasminogen activator - Urinary plasminogen activator
