Prolactin receptor
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prolactin receptor
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| Identifiers | |
| Symbol | PRLR |
| HUGO | 9446 |
| Entrez | 5618 |
| OMIM | 176761 |
| RefSeq | NM_000949 |
| UniProt | P16471 |
| Other data | |
| Locus | Chr. 5 p13-p12 |
The prolactin receptor—encoded by a gene on Chromosome 5p13-14—interacts with the prolactin molecule as a transmembrane receptor.
Thus it contains an extracellular region that binds prolactin, a transmembrane regions, and a cytoplasmatic region.
A specific second messenger has not yet been identified.
There may be variations among different tissue prolactin receptors.
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CRH - FSH - LHRH - TRH - Somatostatin
Vasopressin (1A, 1B, 2) - Oxytocin - LHCG - GH - Prolactin - TSH
Angiotensin - Atrial natriuretic factor - Bradykinin - Calcitonin - Calcitonin gene-related peptide - Cholecystokinin - Galanin - Neuropeptide Y - Neurotensin - Opioid (Delta, Kappa, Mu, Sigma, Nociceptin) - Tachykinin - VIP
