Poly vinyl pyrrolidone

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PVP (polyvinyl pyrrolidone, povidone, polyvidone) is a water-soluble polymer made from the monomer N-vinyl pyrrolidone:

1 Registry Numbers and Synonyms
2 Properties
3 Uses
4 Material Safety Data Sheet
5 Cross-linked derivatives
6 See also
7 References

[edit] Registry Numbers and Synonyms

CAS Number: 9003-39-8

Molecular Formula: C6H9NO

Merck 13, 7783

MFCD: MFCD00149016

1-Ethenyl-2-pyrrolidoinone homopolymer (IUPAC); Poly[1-(2-oxo-1-pyrrolidinyl)ethylene]; polyvidone; polyvinylpyrrolidone; PVP; 1-vinyl-2-pyrrolidinone polymer

[edit] Properties

PVP is soluble in water and other polar solvents. In water it has the useful property of Newtonian viscosity. When dry it is a light flaky powder, which readily absorbs up to 18% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings.

[edit] Uses

The monomer is carcinogenic and is extremely toxic to aquatic life. However the polymer PVP in its pure form is so safe that not only it is edible by humans, it was used as a blood plasma expander for trauma victims after the first half of 20th century.

It is used as a binder in many pharmaceutical tablets; being completely inert to humans, it simply passes through. PVP added to Iodine forms a complex; in solution it is known under the trade name Betadine.

PVP binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers.

PVP is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that you have to moisten, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some.

As a food additive, PVP is a stabilizer and has E number E1201. PVPP is E1202.

In molecular biology, PVP can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer.

[edit] Material Safety Data Sheet

MSDS for PVP from EMD Chemicals

[edit] Cross-linked derivatives

A cross-linked form of PVP is also used as a disintegrant in pharmaceutical tablets. ¹ cross linked polyvinyl pyrrolidone (PVPP) - is used to bind impurities to remove them from solutions. Basically, PVPP is a more highly cross-linked version of PVP, which makes it insoluble in water. This means that it can be used to extract impurities by filtration. This polymer is used to filter bitter compounds from drinks and can even be taken as a tablet to absorb compounds causing diarrhoea. (Cf. bone char, charcoal.)