Phosphatidylserine
From Wikipedia, the free encyclopedia
Phosphatidylserine | |
---|---|
Identifiers | |
CAS number | [ | ]
PubChem | |
Properties | |
Molecular formula | C13H24NO10P |
Molar mass | 385.304 |
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
Phosphatidylserine is a phospholipid nutrient found in fish, green leafy vegetables, soybeans and rice, and is essential for the normal functioning of neuronal cell membranes. In apoptosis, phosphatidylserine is transferred to the outer leaflet of the plasma membrane. This is part of the process by which the cell is targeted for phagocytosis. Phosphatidylserine (PS) has been used to slow cognitive decline in early-onset Alzheimer's disease.[citation needed] The substance is sold as a dietary supplement to people who believe they can benefit from an increased intake.
The dietary supplement was originally processed from cow brains. Prion disease scares in the 1990s outlawed this process, and soon a soy-based alternative was developed.[citation needed]PS sold now is made from plants instead of animals.
[edit] External links
- DrugBank info page
- Phosphatidylserine and Cognitive Dysfunction and Dementia
- MeSH Phosphatidylserines
Glycerophospholipids/Phosphoglycerides: Phosphatidylethanolamine - Phosphatidylcholine - Dipalmitoylphosphatidylcholine - Cardiolipin - Phosphatidylserine - Ether lipids (Plasmalogen, Platelet-activating factor)
Phosphatidylinositol - Glycophosphatidylinositol - Phosphatidylinositol 3-phosphate - Phosphatidylinositol (3,4)-bisphosphate - Phosphatidylinositol (3,5)-bisphosphate - Phosphatidylinositol (4,5)-bisphosphate - Phosphatidylinositol (3,4,5)-trisphosphate