Talk:Personalized medicine

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[edit] Gleevec

I disagree that use of imatinib mesylate (the real name of Gleevec) constitutes "personalised medicine". This is targeted therapy, but that is not the same as the loaded and horrible term "personalised medicine". It would be if every CML patient had his bcr/abl checked for particular resistance mutations and assigned imatinib, nilotinib or dasatinib as per the findings. That is not the case. JFW | T@lk 16:32, 27 September 2006 (UTC)

Unfortunately, I have to disagree with the previous post. Pesonalized medicine is about the right treatment, the right prevention, the right medicine, for the right person. Gleevec is a targeted therapy, in that it only works on "the right type" of cancer. Moreover it goes directly to the heart of what personalized medicine is. It is the moleculary evaluated patient, with the molecularly evaluated disease, and the molecularly designed treatment. Case in point: Gleevec, Tarceva, Amplichip all have pathophysiology molecularly evaluated, with molecularly evaluated patients, and although sometimes the medicines are used inappropriately by uneducated physicians, the majority are used appropriately on the the "right person". Most CML in the US is evaluated for the BCR-ABL fusion gene. Perhaps not in other countries, but absolutely in the US. So it should be included here. SARM | T@lk 09:32, 08 December 2006 (UTC)